CJC 1295 DAC, a long acting GHRH polypeptide, causes the anterior pituitary’s somatotropes to release growth hormone. DAC conjugated CJC 1295, makes this GHRH have a half life of more than a week (approx. 8 days). GHRH is released in pulses in the body which alternate with corresponding pulses of somatostatin (growth-hormone inhibiting-hormone). Ghrelin, released from the gut which circulates and acts as a hunger hormone, has synergistic activity in the body with GHRH and also suppresses somatostatin to make way for the GHRH pulse. Studies shows that combining GHRP with CJC 1295 DAC, significantly increase the release of GH and IGF-1 production.